Viruses / Vaccines 2
Comments
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This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Infections are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.0 -
tempo_n_groove said:Has the news pretty much stopped reporting on this because we pretty much stopped talking about this.
America Is Staring Down Its First So What? Wave
https://www.theatlantic.com/health/archive/2022/04/ba2-omicron-variant-covid-surge/629474/?fbclid=IwAR29caJety8AUfHgvOy46_NLeBYCHNoJoVSAYWMxlrG_SqcfCqd6E4oldnQ
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2024 Napa, Wrigley, Wrigley0 -
Those are Massachusetts numbers. Also, Monday's report only counts for Friday. Yesterday's three-day death total for Saturday, Sunday, and Monday was 12.tempo_n_groove said:
This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Positive tests are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.
More importantly, I was referring to Boston specifically, which is more densely populated than where you and I live. The uptick in case counts there indicates that masking and social distancing might need to be re-enforced at larger indoor gatherings in Knucklehead City.I SAW PEARL JAM0 -
The Atlantic has been in code red worse case scenario this whole time.OnWis97 said:tempo_n_groove said:Has the news pretty much stopped reporting on this because we pretty much stopped talking about this.America Is Staring Down Its First So What? Wave
https://www.theatlantic.com/health/archive/2022/04/ba2-omicron-variant-covid-surge/629474/?fbclid=IwAR29caJety8AUfHgvOy46_NLeBYCHNoJoVSAYWMxlrG_SqcfCqd6E4oldnQ0 -
You have to test to get positive results and I don't know anyone testing unless they are sick nowadays.dankind said:
Those are Massachusetts numbers. Also, Monday's report only counts for Friday. Yesterday's three-day death total for Saturday, Sunday, and Monday was 12.tempo_n_groove said:
This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Positive tests are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.
More importantly, I was referring to Boston specifically, which is more densely populated than where you and I live. The uptick in case counts there indicates that masking and social distancing might need to be re-enforced at larger indoor gatherings in Knucklehead City.0 -
Cool. All I know is that I'm no longer going into the Boston office tomorrow.tempo_n_groove said:
You have to test to get positive results and I don't know anyone testing unless they are sick nowadays.dankind said:
Those are Massachusetts numbers. Also, Monday's report only counts for Friday. Yesterday's three-day death total for Saturday, Sunday, and Monday was 12.tempo_n_groove said:
This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Positive tests are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.
More importantly, I was referring to Boston specifically, which is more densely populated than where you and I live. The uptick in case counts there indicates that masking and social distancing might need to be re-enforced at larger indoor gatherings in Knucklehead City.I SAW PEARL JAM0 -
Of course Boston is going to be the epicenter of things here in MA. I posted state numbers because they obviously include Boston and overall state numbers are staying steady and pretty low in terms of all the metrics besides positive tests. And it had been a long while since a zero on daily death report.dankind said:
Those are Massachusetts numbers. Also, Monday's report only counts for Friday. Yesterday's three-day death total for Saturday, Sunday, and Monday was 12.tempo_n_groove said:
This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Positive tests are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.
More importantly, I was referring to Boston specifically, which is more densely populated than where you and I live. The uptick in case counts there indicates that masking and social distancing might need to be re-enforced at larger indoor gatherings in Knucklehead City.
Just seems that the metric of case numbers isn't the most important one to be concerned with, severity of illness is definitely far less in vast majority of cases now compared with 2020 and 2021, so if we can avoid another variant that causes severe illness, we may be in a decent place, the thing isn't ever going away, but if it becomes like a cold which seems like what's happening, we will be OK generally speaking.This weekend we rock Portland0 -
Well, since your feeling fairly sanguine, I might have some JWIII tix for you if no one else in my family wants to take the boy.Poncier said:
Of course Boston is going to be the epicenter of things here in MA. I posted state numbers because they obviously include Boston and overall state numbers are staying steady and pretty low in terms of all the metrics besides positive tests. And it had been a long while since a zero on daily death report.dankind said:
Those are Massachusetts numbers. Also, Monday's report only counts for Friday. Yesterday's three-day death total for Saturday, Sunday, and Monday was 12.tempo_n_groove said:
This is the news I like to hear. Bravo.Poncier said:
But hospitalizations are staying relatively low, and Monday the report contained zero deaths.dankind said:Positive tests are up in Boston again.
And of 237 folks in the state currently in hospital with Covid, only 82 were admitted because of Covid, other 155 are in for something else and then tested positive.
So, the latest sub variant of Omicron while increasing case numbers (but not nearly at the rate the original Omicron surge did) is definitely far milder than the original strain and Delta variants.
We're going to have to live with its existence, but in its current form we should be able to.
More importantly, I was referring to Boston specifically, which is more densely populated than where you and I live. The uptick in case counts there indicates that masking and social distancing might need to be re-enforced at larger indoor gatherings in Knucklehead City.
Just seems that the metric of case numbers isn't the most important one to be concerned with, severity of illness is definitely far less in vast majority of cases now compared with 2020 and 2021, so if we can avoid another variant that causes severe illness, we may be in a decent place, the thing isn't ever going away, but if it becomes like a cold which seems like what's happening, we will be OK generally speaking.
I was in the unsure camp before, but now, I sure as fuck ain't going.
Maybe he'll come back and play an outdoor venue sometime.I SAW PEARL JAM0 -
Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.This weekend we rock Portland0 -
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!Post edited by dankind onI SAW PEARL JAM0 -
dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
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Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
US experts wrestle with how to update COVID-19 vaccinesBy MATTHEW PERRONE11 mins ago
WASHINGTON (AP) — More than two years into the COVID-19 pandemic, U.S. health officials are beginning to grapple with how to keep the vaccines updated to best protect Americans from the ever-changing coronavirus.
On Wednesday, a panel of vaccine advisers to the Food and Drug Administration spent hours debating key questions for revamping the shots and conducting future booster campaigns. They didn't reach any firm conclusions.
The questions facing the experts included: How often to update the vaccines against new strains, how effective they should be to warrant approval and whether updates should be coordinated with global health authorities.
Last week, the FDA authorized a fourth dose of the Pfizer or Moderna vaccines for anyone 50 or older and for some younger people with severely weakened immune systems. It’s an effort to get ahead of another possible surge.
But the FDA's vaccine chief Dr. Peter Marks acknowledged at the meeting “we simply can’t be boosting people as frequently as we are.” He called the latest booster update a “stopgap” measure to protect vulnerable Americans while regulators decide whether and how to tweak the current vaccines.
Marks cautioned that waning vaccine protection, new variants and colder weather in the fall could raise the risk of more surges.
“Our goal here is to stay ahead of future variants and outbreaks and ensure we do our best to reduce the toll of disease and death due to COVID-19,” said Marks, adding that he expects more meetings of the vaccine panel in coming months.
Some of the key questions the panel discussed:
HOW SHOULD THE U.S. DECIDE WHEN TO LAUNCH FUTURE ROUNDS OF BOOSTER SHOTS?
One area where experts appeared to agree is that vaccines should be judged on their ability to prevent severe disease that leads to hospitalization and death.
“We need to focus on the worst case, which is severe disease, and we need to change strains when we’re losing that battle,” said Dr. Mark Sawyer of the University of California San Diego.
By that measure, the current vaccines have held up remarkably well.
During the last omicron-driven surge, two vaccine doses were nearly 80% effective against needing a breathing machine or death — and a booster pushed that protection to 94%, federal scientists recently reported.
But only about half of Americans eligible for a third shot have gotten one. And many experts said it was unsustainable to continue asking Americans to get boosted every few months.
A panelist from the Centers for Disease Control and Prevention suggested that the 80% protection from severe disease could become the standard for evaluating the vaccines.
"I think we may have to accept that level of protection and then use other alternative ways to protect individuals with therapeutics and other measures,” said Dr. Amanda Cohn, CDC's chief medical officer.
Presentations at the meeting by government health officials and independent researchers underscored the challenges of predicting when the next major COVID-19 variant might appear.
Trevor Bedford, a disease modeler with the Fred Hutchinson Cancer Research Center, said a major new strain like omicron could emerge anywhere from every 1.5 years to once a decade, based on currently available data. Given that unpredictability, researchers will need methods to quickly determine whether current vaccines work against emerging variants.
WHAT’S THE PROCESS FOR UPDATING VACCINES TO ADDRESS NEW VARIANTS?
All three COVID-19 vaccines now used in the U.S. are based on the original coronavirus version that emerged in late 2019. Updating the vaccines will be a complex task, likely requiring coordination between the FDA, manufacturers and global health authorities.
To speed the vaccines to market, the FDA relied on research shortcuts to judge effectiveness, mainly looking at their early impact on the immune system's antibody levels. A number of panelists said Wednesday they wanted more rigorous data from studies that track patients over time to see who gets sick or dies.
But that approach would likely be too time consuming.
“We’re looking at a conundrum here in that it’s going to hard to generate all the data we want in short order when a new variant emergences,” said Dr. Ofer Levy of Harvard Medical School.
A representative for the U.S. Biomedical Advanced Research and Development Authority laid out the narrow window that manufacturers could face to reformulate, study and mass produce an updated vaccine by September.
“If you’re not on your way to a clinical trial by the beginning of May, I think it’s going to be very difficult to have enough product across manufacturers to meet demand,” said Robert Johnson, deputy assistant secretary of BARDA.
The process for updating annual flu vaccines offers one possible model, as laid out by a representative from the World Health Organization.
Twice a year, WHO experts recommend updates to flu vaccines to target emerging strains. The FDA then brings those recommendations to its own vaccine panel, which votes on whether they make sense for the U.S., setting the stage for manufacturers to tweak their shots and begin mass production.
But COVID-19 hasn’t yet fallen into a predictable pattern like the flu. And as the coronavirus evolves, different strains may become dominant in different regions of the world.
Several experts said they would need more meetings with more data and proposals from the FDA to decide on a strategy.
“We’ve never been here before. We’re all working together to do the best we can and it’s very complex,” said Oveta Fuller of the University of Michigan's Medical School.
___
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
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Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.I SAW PEARL JAM0 -
dankind said:
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.
well, I dont hear much difference between ws and solo, if that "helps".
_____________________________________SIGNATURE________________________________________________
Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
FORGET THE STUDIO OUTPUT. JUST GO. IT WILL (MAY) BE THE BEST SHOW OF YOUR LIFE.dankind said:
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.By The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0 -
White Stripes Coney Island 2005 is quite possibly the best show I've ever seen, but so much of that was because of Meg for me.HughFreakingDillon said:
FORGET THE STUDIO OUTPUT. JUST GO. IT WILL (MAY) BE THE BEST SHOW OF YOUR LIFE.dankind said:
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.
Maybe there'll be some YouTube videos of the concerts on this tour before Boston to see if it's worth checking out.
Considering that I skipped the trip into my Boston office today because of case counts in the city and that the indoor show is only 10 days away in that same city, I think that I would have to heavily self-medicate to make it there--and that's not very healthy.I SAW PEARL JAM0 -
5mil people presently have it here. Its highest its ever been.
this song is meant to be called i got shit,itshould be called i got shit tickets-hartford 06 -0 -
right, forgot about the anxiety issues. I hear ya.dankind said:
White Stripes Coney Island 2005 is quite possibly the best show I've ever seen, but so much of that was because of Meg for me.HughFreakingDillon said:
FORGET THE STUDIO OUTPUT. JUST GO. IT WILL (MAY) BE THE BEST SHOW OF YOUR LIFE.dankind said:
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.
Maybe there'll be some YouTube videos of the concerts on this tour before Boston to see if it's worth checking out.
Considering that I skipped the trip into my Boston office today because of case counts in the city and that the indoor show is only 10 days away in that same city, I think that I would have to heavily self-medicate to make it there--and that's not very healthy.By The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0 -
I was at that 2005 show. I agree it was amazing.dankind said:
White Stripes Coney Island 2005 is quite possibly the best show I've ever seen, but so much of that was because of Meg for me.HughFreakingDillon said:
FORGET THE STUDIO OUTPUT. JUST GO. IT WILL (MAY) BE THE BEST SHOW OF YOUR LIFE.dankind said:
It's more that I don't want to take the boy. He's just too immature. As Hank Hill would say, "That boy ain't right."mickeyrat said:dankind said:
At this point, I'm hoping he doesn't know the date and asks me sometime in May when the JWIII concert is, and then I can just pretend that I forgot all about it.Poncier said:Mask up and take the kid.
I have family stuff that day, so can't go even if I wanted to.
Plus looking at the venue map on Ticketmaster, the show has a lot unsold, so you can probably keep your social distance.
I forget about so much these days that it's not a stretch. I'm a terrible liar, though. I need a Costanza lesson!
if you're 50, get the 4th booster.
Case counts going up just gives me another reason not to take him. And unless it's a White Stripes reunion in disguise, I have zero personal interest in going. I don't know any of his solo songs, though I do like the more recent ones that I've heard through shitty formats (YouTube, etc.).
I'll likely donate the tickets.
Maybe there'll be some YouTube videos of the concerts on this tour before Boston to see if it's worth checking out.
Considering that I skipped the trip into my Boston office today because of case counts in the city and that the indoor show is only 10 days away in that same city, I think that I would have to heavily self-medicate to make it there--and that's not very healthy.
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Man, china seems like a fun place right now.0
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