Viruses / Vaccines 2
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mrussel1 said:static111 said:nicknyr15 said:Ledbetterman10 said:Anyone else following this "COVID-Zero" lockdown in Shanghai, China? It's insane how those people are being treated.0
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COVID shots still work but researchers hunt new improvementsBy LAURAN NEERGAARDYesterday
COVID-19 vaccinations are at a critical juncture as companies test whether new approaches like combination shots or nasal drops can keep up with a mutating coronavirus — even though it’s not clear if changes are needed.
Already there’s public confusion about who should get a second booster now and who can wait. There's also debate about whether pretty much everyone might need an extra dose in the fall.
“I’m very concerned about booster fatigue” causing a loss of confidence in vaccines that still offer very strong protection against COVID-19’s worst outcomes, said Dr. Beth Bell of the University of Washington, an adviser to the U.S. Centers for Disease Control and Prevention.
Despite success in preventing serious illness and death, there's growing pressure to develop vaccines better at fending off milder infections, too — as well as options to counter scary variants.
“We go through a fire drill it seems like every quarter, every three months or so” when another mutant causes frantic tests to determine if the shots are holding, Pfizer vaccine chief Kathrin Jansen told a recent meeting of the New York Academy of Sciences.
Yet seeking improvements for the next round of vaccinations may seem like a luxury for U.S. families anxious to protect their littlest children — kids under 5 who are not yet eligible for a shot. Moderna's Dr. Jacqueline Miller told The Associated Press that its application to give two low-dose shots to the youngest children would be submitted to the Food and Drug Administration “fairly soon.” Pfizer hasn't yet reported data on a third dose of its extra-small shot for tots, after two didn't prove strong enough.
COMBINATION SHOTS MAY BE NEXT
The original COVID-19 vaccines remain strongly protective against serious illness, hospitalization and death, especially after a booster dose, even against the most contagious variants.
Updating the vaccine recipe to match the latest variants is risky, because the next mutant could be completely unrelated. So companies are taking a cue from the flu vaccine, which offers protection against three or four different strains in one shot every year.
Moderna and Pfizer are testing 2-in-1 COVID-19 protection that they hope to offer this fall. Each “bivalent” shot would mix the original, proven vaccine with an omicron-targeted version.
Moderna has a hint the approach could work. It tested a combo shot that targeted the original version of the virus and an earlier variant named beta — and found vaccine recipients developed modest levels of antibodies capable of fighting not just beta but also newer mutants like omicron. Moderna now is testing its omicron-targeted bivalent candidate.
But there's a looming deadline. FDA's Dr. Doran Fink said if any updated shots are to be given in the fall, the agency would have to decide on a recipe change by early summer.
DON’T EXPECT BOOSTERS EVERY FEW MONTHS
For the average person, two doses of the Pfizer or Moderna vaccine plus one booster — a total of three shots — “gets you set up” and ready for what may become an annual booster, said Dr. David Kimberlin, a CDC adviser from the University of Alabama at Birmingham.
After that first booster, CDC data suggests an additional dose offers most people an incremental, temporary benefit.
Why the emphasis on three shots? Vaccination triggers development of antibodies that can fend off coronavirus infection but naturally wane over time. The next line of defense: Memory cells that jump into action to make new virus-fighters if an infection sneaks in. Rockefeller University researchers found those memory cells become more potent and able to target more diverse versions of the virus after the third shot.
Even if someone who's vaccinated gets a mild infection, thanks to those memory cells “there's still plenty of time to protect you against severe illness,” said Dr. Paul Offit of the Children’s Hospital of Philadelphia.
But some people — those with severely weakened immune systems — need more doses up-front for a better chance at protection.
And Americans 50 and older are being offered a second booster, following similar decisions by Israel and other countries that offer the extra shot to give older people a little more protection.
The CDC is developing advice to help those eligible decide whether to get an extra shot now or wait. Among those who might want a second booster sooner are the elderly, people with health problems that make them particularly vulnerable, or who are at high risk of exposure from work or travel.
COULD NASAL VACCINES BLOCK INFECTION?
It’s hard for a shot in the arm to form lots of virus-fighting antibodies inside the nose where the coronavirus latches on. But a nasal vaccine might offer a new strategy to prevent infections that disrupt people’s everyday lives even if they’re mild.
“When I think about what would make me get a second booster, I actually would want to prevent infection,” said Dr. Grace Lee of Stanford University, who chairs CDC’s immunization advisory committee. “I think we need to do better.”
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mace1229 said:mrussel1 said:static111 said:nicknyr15 said:Ledbetterman10 said:Anyone else following this "COVID-Zero" lockdown in Shanghai, China? It's insane how those people are being treated.wonder if folks here have considered this, especially in light of what NYC faced, given the population of China and its largest cities...Content Preview Shanghai — 23.4 million people Beijing — 18.8 million people Tianjin — 12.8 million people Shenzhen — 12.7 million people Guangzhou — 11.6 million people Chengdu — 10.2 million people Chongqing — 8.5 million people Dongguan — 8.3 million people Shenyang — 7.9 million people Wuhan — 7.9 million peoplewonder how many beds they have in each location to handle case counts without such a heavy hand._____________________________________SIGNATURE________________________________________________
Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
mace1229 said:mrussel1 said:static111 said:nicknyr15 said:Ledbetterman10 said:Anyone else following this "COVID-Zero" lockdown in Shanghai, China? It's insane how those people are being treated.0
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It’s fucking China, the world’s largest surveillance state and population control (one child policy, anyone?) conglomeration and we’re supposed to be surprised or outraged? Where have you been since Tiananmen Square?09/15/1998 & 09/16/1998, Mansfield, MA; 08/29/00 08/30/00, Mansfield, MA; 07/02/03, 07/03/03, Mansfield, MA; 09/28/04, 09/29/04, Boston, MA; 09/22/05, Halifax, NS; 05/24/06, 05/25/06, Boston, MA; 07/22/06, 07/23/06, Gorge, WA; 06/27/2008, Hartford; 06/28/08, 06/30/08, Mansfield; 08/18/2009, O2, London, UK; 10/30/09, 10/31/09, Philadelphia, PA; 05/15/10, Hartford, CT; 05/17/10, Boston, MA; 05/20/10, 05/21/10, NY, NY; 06/22/10, Dublin, IRE; 06/23/10, Northern Ireland; 09/03/11, 09/04/11, Alpine Valley, WI; 09/11/11, 09/12/11, Toronto, Ont; 09/14/11, Ottawa, Ont; 09/15/11, Hamilton, Ont; 07/02/2012, Prague, Czech Republic; 07/04/2012 & 07/05/2012, Berlin, Germany; 07/07/2012, Stockholm, Sweden; 09/30/2012, Missoula, MT; 07/16/2013, London, Ont; 07/19/2013, Chicago, IL; 10/15/2013 & 10/16/2013, Worcester, MA; 10/21/2013 & 10/22/2013, Philadelphia, PA; 10/25/2013, Hartford, CT; 11/29/2013, Portland, OR; 11/30/2013, Spokane, WA; 12/04/2013, Vancouver, BC; 12/06/2013, Seattle, WA; 10/03/2014, St. Louis. MO; 10/22/2014, Denver, CO; 10/26/2015, New York, NY; 04/23/2016, New Orleans, LA; 04/28/2016 & 04/29/2016, Philadelphia, PA; 05/01/2016 & 05/02/2016, New York, NY; 05/08/2016, Ottawa, Ont.; 05/10/2016 & 05/12/2016, Toronto, Ont.; 08/05/2016 & 08/07/2016, Boston, MA; 08/20/2016 & 08/22/2016, Chicago, IL; 07/01/2018, Prague, Czech Republic; 07/03/2018, Krakow, Poland; 07/05/2018, Berlin, Germany; 09/02/2018 & 09/04/2018, Boston, MA; 09/08/2022, Toronto, Ont; 09/11/2022, New York, NY; 09/14/2022, Camden, NJ; 09/02/2023, St. Paul, MN; 05/04/2024 & 05/06/2024, Vancouver, BC; 05/10/2024, Portland, OR;
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the country that executes people for importing american movies does not surprise me in the least what they are doing.By The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0
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Gross.I SAW PEARL JAM0
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Wait wait wait...people are seriously comparing what's happing in fucking China to our mandates in the US? Is that seriously happening here?
Hoooo boy
www.myspace.com0 -
The Juggler said:Wait wait wait...people are seriously comparing what's happing in fucking China to our mandates in the US? Is that seriously happening here?
Hoooo boyBy The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0 -
HughFreakingDillon said:The Juggler said:Wait wait wait...people are seriously comparing what's happing in fucking China to our mandates in the US? Is that seriously happening here?
Hoooo boywww.myspace.com0 -
The Juggler said:HughFreakingDillon said:The Juggler said:Wait wait wait...people are seriously comparing what's happing in fucking China to our mandates in the US? Is that seriously happening here?
Hoooo boy
And I can't imagine the frustration of being a small business owner and being told that I can't do business for people to buy groceries because my square footage doesn't fall into the category of an essential business, but people can go to Best Buy to get a tv.
there was a lot of stupidity to a lot of these rules; I get that they couldn't specify different rules for every single business. But still...a tattoo shop that is as clean and sanitary as a dentist's office not being allowed to do business for a year? that would be maddening as that business owner.
so I get it when people are skeptical of the powers that be telling us that these rules were based science, when a lot of them clearly weren't; they were based in science AND economics. So just come out and say that. They didn't. Not here at least. so when the trust is lost on little items like that, trust can ultimately be lost completely and then it turns into "trudeau is a dictator". again, I don't agree with it, but I get how it happens.By The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0 -
mrussel1 said:mace1229 said:mrussel1 said:static111 said:nicknyr15 said:Ledbetterman10 said:Anyone else following this "COVID-Zero" lockdown in Shanghai, China? It's insane how those people are being treated.0
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HughFreakingDillon said:The Juggler said:HughFreakingDillon said:The Juggler said:Wait wait wait...people are seriously comparing what's happing in fucking China to our mandates in the US? Is that seriously happening here?
Hoooo boy
And I can't imagine the frustration of being a small business owner and being told that I can't do business for people to buy groceries because my square footage doesn't fall into the category of an essential business, but people can go to Best Buy to get a tv.
there was a lot of stupidity to a lot of these rules; I get that they couldn't specify different rules for every single business. But still...a tattoo shop that is as clean and sanitary as a dentist's office not being allowed to do business for a year? that would be maddening as that business owner.
so I get it when people are skeptical of the powers that be telling us that these rules were based science, when a lot of them clearly weren't; they were based in science AND economics. So just come out and say that. They didn't. Not here at least. so when the trust is lost on little items like that, trust can ultimately be lost completely and then it turns into "trudeau is a dictator". again, I don't agree with it, but I get how it happens.www.myspace.com0 -
Many people on the right think that the Covid response was testing the waters for a China style social credit system, so therefore if you don't show the appropriate level of outrage at what's going on, it means we'll support the credit system here.
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Go Beavers said:Many people on the right think that the Covid response was testing the waters for a China style social credit system, so therefore if you don't show the appropriate level of outrage at what's going on, it means we'll support the credit system here.
If you want this class system here in the US I say please watch Black Mirror. That is about the best thing I can use for what is coming. 1984 and Fahrenheit 451 may be dated for kids but the show isn't...0 -
I'm getting my 2nd booster today....went with Pfizer after reading about it
First round was J&J
1st boost ModernaRemember the Thomas Nine !! (10/02/2018)
The Golden Age is 2 months away. And guess what….. you’re gonna love it! (teskeinc 11.19.24)
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2016: Lexington, Wrigley #1; 2018: Wrigley, Wrigley, Boston, Boston
2020: Oakland, Oakland: 2021: EV Ohana, Ohana, Ohana, Ohana
2022: Oakland, Oakland, Nashville, Louisville; 2023: Chicago, Chicago, Noblesville
2024: Noblesville, Wrigley, Wrigley, Ohana, Ohana; 2025: Pitt1, Pitt20 -
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Oh joy. One strain 10% fatality rate, the other 1%. How many will refuse vaccination when the time comes? Stop the world, I want to get off.
Massachusetts health authorities said Wednesday that they confirmed a case of a rare and sometimes serious viral illness called monkeypox — the first infection identified in the United States this year amid a rash of cases outside the disease’s typical territory.
Monkeypox, which can be passed to animals and humans, is usually found in Central and West Africa. But health authorities in Europe have confirmed more than a dozen cases this month and are investigating dozens more. The two latest infections confirmed in the United Kingdom “have no travel links” to a place where monkeypox is regularly found, officials said, suggesting the virus may be spreading through the community.
Scientists are trying to answer questions about the outbreak of a disease not known to spread easily between humans. The fact that cases are emerging in several countries at once — with signs of “sustained” spread in people — is striking, said Aris Katzourakis, a professor of evolution and genomics at the University of Oxford.
The disease can spread through contact with animals, infected people and materials used by infected people, health authorities say. Examples listed by the CDC include contact with bodily fluids, contact with monkeypox sores and infection through “respiratory droplets” in a “close setting” such as a shared household.
Monkeypox can be deadly, but two major strains of the virus pose different risks. About 1 in 10 people infected with a Congo Basin strain have been found to die, according to the World Health Organization, while a West African strain appeared to be fatal for about 1 in 100 people infected.
That milder strain is the one infecting people who were hospitalized in the United Kingdom, health authorities said. It is not clear what strain the Massachusetts patient contracted.
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Fuck. I spent a lot of time last might doom scrolling when I saw it trending. This is fucked up.By The Time They Figure Out What Went Wrong, We'll Be Sitting On A Beach, Earning Twenty Percent.0
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