The coronavirus
Comments
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Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:F Me In The Brain said:You walk right back in and piss around about China.
Nothing has changed.
Do you live there? Are you of Chinese background?
Did you read what I shared in that article and did you watch that video?
Why are you not allowing me to be critical of China? Why are you criticising me for criticising China?
So you have no issue with their secrecy which led to thousands of innocent people dying around the world?
Why did they not alert the WHO and other countries and stop flights leaving Wuhan when they first knew of this new virus? Doing so would have prevented this outbreak.
I don't understand you and others here.
I'd be more than glad to buy Australian made clothes and appliances. Even if I have to pay more.
This is the world's fault for being greedy (in wanting cheap labour).
You pay more for domestic goods. And the North Korean people suffer under an oppressive regime. It's economic inequality on a massive multinational scale.
Staying in the TPP agreement would have been a good start...0 -
CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:F Me In The Brain said:You walk right back in and piss around about China.
Nothing has changed.
Do you live there? Are you of Chinese background?
Did you read what I shared in that article and did you watch that video?
Why are you not allowing me to be critical of China? Why are you criticising me for criticising China?
So you have no issue with their secrecy which led to thousands of innocent people dying around the world?
Why did they not alert the WHO and other countries and stop flights leaving Wuhan when they first knew of this new virus? Doing so would have prevented this outbreak.
I don't understand you and others here.
I'd be more than glad to buy Australian made clothes and appliances. Even if I have to pay more.
This is the world's fault for being greedy (in wanting cheap labour).
You pay more for domestic goods. And the North Korean people suffer under an oppressive regime. It's economic inequality on a massive multinational scale.
Staying in the TPP agreement would have been a good start...Adelaide 17/11/2009, Melbourne 20/11/2009, Sydney 22/11/2009, Melbourne (Big Day Out Festival) 24/01/20140 -
Thoughts_Arrive said:MayDay10 said:Thoughts_Arrive said:You know why I am mad?
My friend's fiance just gave birth to their first child and she is so isolated because we are not allowed out of our homes.
She would love to go to mother's groups and get support from new mothers and do baby yoga and go for a walk with a pram.
But she's seriously stressed and isolated. She's on her own with her baby.
She reached out on Facebook asking if anyone has baby paracetamol as her baby is unwell and none is available at her local pharmacies because greedy idiots stockpiled. All this because China did not alert the world.
We dont need to invent something to levy blame on. Things arent always so easy and black and white... even though the human mind seeks that clarity. At some point, when this is over, the international committee will figure it out and hopefully work together to prevent this from happening again.
Everything I have read from reputable sources says that there is no way this virus is man-made.
Why does the CCP allow unhygienic wet markets to exist?
The CCP needs to change its behaviour to prevent this happening again.
SARS, swine flu, MERS, Covid-19, all from China thanks to the CCP.
Good question: why don't rural areas in a developing economy have widespread access to modern refrigeration and established food distribution channels?
Could it be due to decades of protectionist and isolationist foreign policy?
Will continuing these policies lead to more or less pandemic outbreaks?
🐔 /🥚 ?0 -
Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:F Me In The Brain said:You walk right back in and piss around about China.
Nothing has changed.
Do you live there? Are you of Chinese background?
Did you read what I shared in that article and did you watch that video?
Why are you not allowing me to be critical of China? Why are you criticising me for criticising China?
So you have no issue with their secrecy which led to thousands of innocent people dying around the world?
Why did they not alert the WHO and other countries and stop flights leaving Wuhan when they first knew of this new virus? Doing so would have prevented this outbreak.
I don't understand you and others here.
I'd be more than glad to buy Australian made clothes and appliances. Even if I have to pay more.
This is the world's fault for being greedy (in wanting cheap labour).
You pay more for domestic goods. And the North Korean people suffer under an oppressive regime. It's economic inequality on a massive multinational scale.We have been living for 20 years under a false economy, by incorrectly believing we were buying cheap products from China, a country that does not check for food safety like the advanced countries do. If we were to add the total cost of this pandemic onto the cheap TVs and clothes we’ve been buying from China, we would get a truer cost of what they cost the world monetarily, let alone lives.
We need to begin to hold all our trading partners to the strict safety regulation that the modern nations have.
Hang in there TA, we are all stressed and concerned.Post edited by Lerxst1992 on0 -
Thank you Lerxst1992.
Very good point you made.Adelaide 17/11/2009, Melbourne 20/11/2009, Sydney 22/11/2009, Melbourne (Big Day Out Festival) 24/01/20140 -
CM189191 said:Thoughts_Arrive said:MayDay10 said:Thoughts_Arrive said:You know why I am mad?
My friend's fiance just gave birth to their first child and she is so isolated because we are not allowed out of our homes.
She would love to go to mother's groups and get support from new mothers and do baby yoga and go for a walk with a pram.
But she's seriously stressed and isolated. She's on her own with her baby.
She reached out on Facebook asking if anyone has baby paracetamol as her baby is unwell and none is available at her local pharmacies because greedy idiots stockpiled. All this because China did not alert the world.
We dont need to invent something to levy blame on. Things arent always so easy and black and white... even though the human mind seeks that clarity. At some point, when this is over, the international committee will figure it out and hopefully work together to prevent this from happening again.
Everything I have read from reputable sources says that there is no way this virus is man-made.
Why does the CCP allow unhygienic wet markets to exist?
The CCP needs to change its behaviour to prevent this happening again.
SARS, swine flu, MERS, Covid-19, all from China thanks to the CCP.
Good question: why don't rural areas in a developing economy have widespread access to modern refrigeration and established food distribution channels?
Could it be due to decades of protectionist and isolationist foreign policy?
Will continuing these policies lead to more or less pandemic outbreaks?
🐔 /🥚 ?
But what about stopping people from eating Pangolins and bats?Adelaide 17/11/2009, Melbourne 20/11/2009, Sydney 22/11/2009, Melbourne (Big Day Out Festival) 24/01/20140 -
This doctor was just on CNN and wrote this article 15 years ago about the next pandemic. He pointed out the US is worse off now, because we have been down sizing our hospital capacity since 2005. Much in his article is strikingly accurate to what we are facing.
Preparing for the Next Pandemic
List of authors.- Michael T. Osterholm, Ph.D., M.P.H.
May 5, 2005
N Engl J Med 2005; 352:1839-1842
DOI: 10.1056/NEJMp058068Annual influenza epidemics are like Minnesota winters — all are challenges, but some are worse than others. No matter how well we prepare, some blizzards take quite a toll. Each year, despite our efforts to increase the rates of influenza vaccination in our most vulnerable populations, unpredictable factors largely determine the burden of influenza disease and related deaths. During a typical year in the United States, 30,000 to 50,000 persons die as a result of influenzavirus infection, and the global death toll is about 20 to 30 times as high as the toll in this country. We usually accept this outcome as part of the cycle of life. Only when a vaccine shortage occurs or young children die suddenly does the public demand that someone step forward to change the course of the epidemic. Unfortunately, the fragile and limited production capacity of our 1950s egg-based technology for producing influenza vaccine and the lack of a national commitment to universal annual influenza vaccination mean that influenza epidemics will continue to present a substantial public health challenge for the foreseeable future.
An influenza pandemic has always been a great global infectious-disease threat. There have been 10 pandemics of influenza A in the past 300 years. A recent analysis showed that the pandemic of 1918 and 1919 killed 50 million to 100 million people,1 and although its severity is often considered anomalous, the pandemic of 1830 through 1832 was similarly severe — it simply occurred when the world's population was smaller. Today, with a world population of 6.5 billion — more than three times that in 1918 — even a relatively “mild” pandemic could kill many millions of people.Influenza experts recognize the inevitability of another pandemic. When will it begin? Will it be caused by H5N1, the avian influenzavirus strain currently circulating in Asia? Will its effect rival that of 1918 or be more muted, as was the case in the pandemics of 1957 and 1968? Nobody knows.So how can we prepare? One key step is to rapidly ramp up research related to the production of an effective vaccine, as the Department of Health and Human Services is doing. In addition to clinical research on the immunogenicity of influenza vaccines, urgent needs include basic research on the ecology and biology of influenzaviruses, studies of the epidemiologic role of various animal and bird species, and work on early interventions and risk assessment.2 Equally urgent is the development of cell-culture technology for production of vaccine that can replace our egg-based manufacturing process. Today, making the 300 million doses of influenza vaccine needed annually worldwide requires more than 350 million chicken eggs and six or more months; a cell-culture approach may produce much higher antigen yields and be faster. After such a process was developed, we would also need assured industrial capacity to produce sufficient vaccine for the world's population during the earliest days of an emerging pandemic.Beyond research and development, we need a public health approach that includes far more than drafting of general plans, as several countries and states have done. We need a detailed operational blueprint of the best way to get through 12 to 24 months of a pandemic.What if the next pandemic were to start tonight? If it were determined that several cities in Vietnam had major outbreaks of H5N1 infection associated with high mortality, there would be a scramble to stop the virus from entering other countries by greatly reducing or even prohibiting foreign travel and trade. The global economy would come to a halt, and since we could not expect appropriate vaccines to be available for many months and we have very limited stockpiles of antiviral drugs, we would be facing a 1918-like scenario.Production of a vaccine would take a minimum of six months after isolation of the circulating strain, and given the capacity of all the current international vaccine manufacturers, supplies during those next six months would be limited to fewer than a billion monovalent doses. Since two doses may be required for protection, we could vaccinate fewer than 500 million people — approximately 14 percent of the world's population. And owing to our global “just-in-time delivery” economy, we would have no surge capacity for health care, food supplies, and many other products and services. For example, in the United States today, we have only 105,000 mechanical ventilators, 75,000 to 80,000 of which are in use at any given time for everyday medical care; during a garden-variety influenza season, more than 100,000 are required. In a pandemic, most patients with influenza who needed ventilation would not have access to it.We have no detailed plans for staffing the temporary hospitals that would have to be set up in high-school gymnasiums and community centers — and that might need to remain in operation for one or two years. Health care workers would become ill and die at rates similar to, or even higher than, those in the general public. Judging by our experience with the severe acute respiratory syndrome (SARS), some health care workers would not show up for duty. How would communities train and use volunteers? If the pandemic wave were spreading slowly enough, could immune survivors of an early wave, particularly health care workers, become the primary response corps?Health care delivery systems and managed-care organizations have done little planning for such a scenario. Who, for instance, would receive the extremely limited antiviral agents that will be available? We need to develop a national, and even an international, consensus on the priorities for the use of antiviral drugs well before the pandemic begins. In addition, we have no way of urgently increasing production of critical items such as antiviral drugs, masks for respiratory protection, or antibiotics for the treatment of secondary bacterial infections. Even under today's relatively stable operating conditions, eight different antiinfective agents are in short supply because of manufacturing problems. Nor do we have detailed plans for handling the massive number of dead bodies that would soon exceed our ability to cope with them.What if an H5N1 influenza pandemic began not now but a year from now? We would still need to plan with fervor for local nonmedical as well as medical preparedness. Planning for a pandemic must be on the agenda of every public health agency, school board, manufacturing plant, investment firm, mortuary, state legislature, and food distributor. Health professionals must become much more proficient in “risk communication,” so that they can effectively provide the facts — and acknowledge the unknowns — to a frightened population.3With another year of lead time, vaccine might have a more central role in our response. Although the manufacturing capacity would still be limited, strategies such as developing antigen-sparing formulations — that is, intradermal formulations that take advantage of copious numbers of dendritic cells for antigen processing or formulations including adjuvants to boost the immune response — might extend the vaccine supply. Urgent planning efforts are required to ensure that we have the syringes and other essential equipment, as well as the workforce, for effective delivery. Finally, a detailed plan for vaccine allocation will be needed — before the crisis, not during it.What if the pandemic were 10 years away and we embarked today on a worldwide influenza Manhattan Project aimed at producing and delivering a pandemic vaccine for everyone in the world soon after the onset of sustained human-to-human transmission? In this scenario, we just might make a real difference.The current system of producing and distributing influenza vaccine is broken, both technically and financially. The belief that we can greatly advance manufacturing technology and expand capacity in the normal course of increasing our annual vaccination coverage is flawed. At our current pace, it will take generations for meaningful advances to be made. Our goal should be to develop a new cell-culture–based vaccine that includes antigens that are present in all subtypes of influenzavirus, that do not change from year to year, and that can be made available to the entire world population. We need an international approach to public funding that will pay for the excess production capacity required during a pandemic.Today, public health experts and infectious-disease scientists do not know whether H5N1 avian influenzavirus threatens an imminent pandemic. Most indications, however, suggest that it is just a matter of time: witness the increasing number of H5N1 infections in humans and animals, the documentation of additional small clusters of cases suggestive of near misses with respect to sustained human-to-human transmission, the ongoing genetic changes in the H5N1 Z genotype that have increased its pathogenicity, and the existence in Asia of a genetic-reassortment laboratory — the mix of an unprecedented number of people, pigs, and poultry.It is sobering to realize that in 1968, when the most recent influenza pandemic occurred, the virus emerged in a China that had a human population of 790 million, a pig population of 5.2 million, and a poultry population of 12.3 million; today, these populations number 1.3 billion, 508 million, and 13 billion, respectively. Similar changes have occurred in the human and animal populations of other Asian countries, creating an incredible mixing vessel for viruses. Given this reality, as well as the exponential growth in foreign travel during the past 50 years, we must accept that a pandemic is coming — although whether it will be caused by H5N1 or by another novel strain remains to be seen..Should H5N1 become the next pandemic strain, the resultant morbidity and mortality could rival those of 1918, when more than half the deaths occurred among largely healthy people between 18 and 40 years of age and were caused by a virus-induced cytokine storm (see diagram) that led to the acute respiratory distress syndrome (ARDS).4 The ARDS-related morbidity and mortality in the pandemic of 1918 was on a different scale from those of 1957 and 1968 — a fact that highlights the importance of the virulence of the virus subtype or genotype. Clinical, epidemiologic, and laboratory evidence suggests that a pandemic caused by the current H5N1 strain would be more likely to mimic the 1918 pandemic than those that occurred more recently.5 If we translate the rate of death associated with the 1918 influenzavirus to that in the current population, there could be 1.7 million deaths in the United States and 180 million to 360 million deaths globally. We have an extremely limited armamentarium with which to handle millions of cases of ARDS — one not much different from that available to the front-line medical corps in 1918.Is there anything we can do to avoid this course? The answer is a qualified yes that depends on how everyone, from world leaders to local elected officials, decides to respond. We need bold and timely leadership at the highest levels of the governments in the developed world; these governments must recognize the economic, security, and health threats posed by the next influenza pandemic and invest accordingly. The resources needed must be considered in the light of the eventual costs of failing to invest in such an effort. The loss of human life even in a mild pandemic will be devastating, and the cost of a world economy in shambles for several years can only be imagined.Sign up for the Weekly Table of Contents email.
Each week, receive an email with links to the articles published in the current week's issue of the New England Journal of Medicine.
https://www.nejm.org/doi/full/10.1056/NEJMp058068
0 -
F Me In The Brain said:Is what you do essential?
(For real?)
The other question, I'm sure, is if you can get by without the money....
Tough times. Sorry that this is something you have to consider, Malroth
yes. I could easily go 5 or 6 years without a dime coming in. I do not want to.Give Peas A Chance…0 -
Lerxst1992 said:JW269453 said:bootlegger10 said:nicknyr15 said:josevolution said:nicknyr15 said:josevolution said:Ok so no one is to blame cool so the same can be said of no one takes responsibility correct? And who do you think will take credit when this is over?
Here is my take. Most of the Western World did not do a good job with this. But....There is only one US President right now. There is only one WHite House Administration right now. There is only one Republican controlled Senate.
It is the President's job to lead, and then people follow. The governors were left to fend for themselves and took the lead from the WHite House that this wasn't a big deal and was an impeachment hoax. The different government organizations take the lead from the administration. You can say everyone was unprepared, but there was information out there in Dec/Jan and the leader/party that is in power and asked for votes so they could be in power and in-charge failed to act soon enough. If someone that works for me fails to start a project and the client gets mad, they are calling me because it is my fault and failure to lead.
Sure, we were unprepared before Trump took office. But there were two months practically that the US failed to lead and take action.
Not trying to poke the bear, but in all fairness the only thing the Democrats were focused on was the ongoing impeachment when the initial news broke. Not saying this is their fault, just stating that they had their minds elsewhere as well. I do agree with many of your points.***This is not an endorsement for trump***
It sorta is. This was on March 9th. March 9.See new TweetsTweet
So last year 37,000 Americans died from the common Flu. It averages between 27,000 and 70,000 per year. Nothing is shut down, life & the economy go on. At this moment there are 546 confirmed cases of CoronaVirus, with 22 deaths. Think about that!
Your recollection is vastly inaccurate. Think about that.0 -
I am seeing 5 or 6 new york plated vehicles headed west every night. last couple of days with uhaul equipment too.and that's just between columbus and indy on I-70_____________________________________SIGNATURE________________________________________________
Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
Lerxst1992 said:This doctor was just on CNN and wrote this article 15 years ago about the next pandemic. He pointed out the US is worse off now, because we have been down sizing our hospital capacity since 2005. Much in his article is strikingly accurate to what we are facing.
Preparing for the Next Pandemic
List of authors.- Michael T. Osterholm, Ph.D., M.P.H.
May 5, 2005
N Engl J Med 2005; 352:1839-1842
DOI: 10.1056/NEJMp058068Annual influenza epidemics are like Minnesota winters — all are challenges, but some are worse than others. No matter how well we prepare, some blizzards take quite a toll. Each year, despite our efforts to increase the rates of influenza vaccination in our most vulnerable populations, unpredictable factors largely determine the burden of influenza disease and related deaths. During a typical year in the United States, 30,000 to 50,000 persons die as a result of influenzavirus infection, and the global death toll is about 20 to 30 times as high as the toll in this country. We usually accept this outcome as part of the cycle of life. Only when a vaccine shortage occurs or young children die suddenly does the public demand that someone step forward to change the course of the epidemic. Unfortunately, the fragile and limited production capacity of our 1950s egg-based technology for producing influenza vaccine and the lack of a national commitment to universal annual influenza vaccination mean that influenza epidemics will continue to present a substantial public health challenge for the foreseeable future.
An influenza pandemic has always been a great global infectious-disease threat. There have been 10 pandemics of influenza A in the past 300 years. A recent analysis showed that the pandemic of 1918 and 1919 killed 50 million to 100 million people,1 and although its severity is often considered anomalous, the pandemic of 1830 through 1832 was similarly severe — it simply occurred when the world's population was smaller. Today, with a world population of 6.5 billion — more than three times that in 1918 — even a relatively “mild” pandemic could kill many millions of people.Influenza experts recognize the inevitability of another pandemic. When will it begin? Will it be caused by H5N1, the avian influenzavirus strain currently circulating in Asia? Will its effect rival that of 1918 or be more muted, as was the case in the pandemics of 1957 and 1968? Nobody knows.So how can we prepare? One key step is to rapidly ramp up research related to the production of an effective vaccine, as the Department of Health and Human Services is doing. In addition to clinical research on the immunogenicity of influenza vaccines, urgent needs include basic research on the ecology and biology of influenzaviruses, studies of the epidemiologic role of various animal and bird species, and work on early interventions and risk assessment.2 Equally urgent is the development of cell-culture technology for production of vaccine that can replace our egg-based manufacturing process. Today, making the 300 million doses of influenza vaccine needed annually worldwide requires more than 350 million chicken eggs and six or more months; a cell-culture approach may produce much higher antigen yields and be faster. After such a process was developed, we would also need assured industrial capacity to produce sufficient vaccine for the world's population during the earliest days of an emerging pandemic.Beyond research and development, we need a public health approach that includes far more than drafting of general plans, as several countries and states have done. We need a detailed operational blueprint of the best way to get through 12 to 24 months of a pandemic.What if the next pandemic were to start tonight? If it were determined that several cities in Vietnam had major outbreaks of H5N1 infection associated with high mortality, there would be a scramble to stop the virus from entering other countries by greatly reducing or even prohibiting foreign travel and trade. The global economy would come to a halt, and since we could not expect appropriate vaccines to be available for many months and we have very limited stockpiles of antiviral drugs, we would be facing a 1918-like scenario.Production of a vaccine would take a minimum of six months after isolation of the circulating strain, and given the capacity of all the current international vaccine manufacturers, supplies during those next six months would be limited to fewer than a billion monovalent doses. Since two doses may be required for protection, we could vaccinate fewer than 500 million people — approximately 14 percent of the world's population. And owing to our global “just-in-time delivery” economy, we would have no surge capacity for health care, food supplies, and many other products and services. For example, in the United States today, we have only 105,000 mechanical ventilators, 75,000 to 80,000 of which are in use at any given time for everyday medical care; during a garden-variety influenza season, more than 100,000 are required. In a pandemic, most patients with influenza who needed ventilation would not have access to it.We have no detailed plans for staffing the temporary hospitals that would have to be set up in high-school gymnasiums and community centers — and that might need to remain in operation for one or two years. Health care workers would become ill and die at rates similar to, or even higher than, those in the general public. Judging by our experience with the severe acute respiratory syndrome (SARS), some health care workers would not show up for duty. How would communities train and use volunteers? If the pandemic wave were spreading slowly enough, could immune survivors of an early wave, particularly health care workers, become the primary response corps?Health care delivery systems and managed-care organizations have done little planning for such a scenario. Who, for instance, would receive the extremely limited antiviral agents that will be available? We need to develop a national, and even an international, consensus on the priorities for the use of antiviral drugs well before the pandemic begins. In addition, we have no way of urgently increasing production of critical items such as antiviral drugs, masks for respiratory protection, or antibiotics for the treatment of secondary bacterial infections. Even under today's relatively stable operating conditions, eight different antiinfective agents are in short supply because of manufacturing problems. Nor do we have detailed plans for handling the massive number of dead bodies that would soon exceed our ability to cope with them.What if an H5N1 influenza pandemic began not now but a year from now? We would still need to plan with fervor for local nonmedical as well as medical preparedness. Planning for a pandemic must be on the agenda of every public health agency, school board, manufacturing plant, investment firm, mortuary, state legislature, and food distributor. Health professionals must become much more proficient in “risk communication,” so that they can effectively provide the facts — and acknowledge the unknowns — to a frightened population.3With another year of lead time, vaccine might have a more central role in our response. Although the manufacturing capacity would still be limited, strategies such as developing antigen-sparing formulations — that is, intradermal formulations that take advantage of copious numbers of dendritic cells for antigen processing or formulations including adjuvants to boost the immune response — might extend the vaccine supply. Urgent planning efforts are required to ensure that we have the syringes and other essential equipment, as well as the workforce, for effective delivery. Finally, a detailed plan for vaccine allocation will be needed — before the crisis, not during it.What if the pandemic were 10 years away and we embarked today on a worldwide influenza Manhattan Project aimed at producing and delivering a pandemic vaccine for everyone in the world soon after the onset of sustained human-to-human transmission? In this scenario, we just might make a real difference.The current system of producing and distributing influenza vaccine is broken, both technically and financially. The belief that we can greatly advance manufacturing technology and expand capacity in the normal course of increasing our annual vaccination coverage is flawed. At our current pace, it will take generations for meaningful advances to be made. Our goal should be to develop a new cell-culture–based vaccine that includes antigens that are present in all subtypes of influenzavirus, that do not change from year to year, and that can be made available to the entire world population. We need an international approach to public funding that will pay for the excess production capacity required during a pandemic.Today, public health experts and infectious-disease scientists do not know whether H5N1 avian influenzavirus threatens an imminent pandemic. Most indications, however, suggest that it is just a matter of time: witness the increasing number of H5N1 infections in humans and animals, the documentation of additional small clusters of cases suggestive of near misses with respect to sustained human-to-human transmission, the ongoing genetic changes in the H5N1 Z genotype that have increased its pathogenicity, and the existence in Asia of a genetic-reassortment laboratory — the mix of an unprecedented number of people, pigs, and poultry.It is sobering to realize that in 1968, when the most recent influenza pandemic occurred, the virus emerged in a China that had a human population of 790 million, a pig population of 5.2 million, and a poultry population of 12.3 million; today, these populations number 1.3 billion, 508 million, and 13 billion, respectively. Similar changes have occurred in the human and animal populations of other Asian countries, creating an incredible mixing vessel for viruses. Given this reality, as well as the exponential growth in foreign travel during the past 50 years, we must accept that a pandemic is coming — although whether it will be caused by H5N1 or by another novel strain remains to be seen..Should H5N1 become the next pandemic strain, the resultant morbidity and mortality could rival those of 1918, when more than half the deaths occurred among largely healthy people between 18 and 40 years of age and were caused by a virus-induced cytokine storm (see diagram) that led to the acute respiratory distress syndrome (ARDS).4 The ARDS-related morbidity and mortality in the pandemic of 1918 was on a different scale from those of 1957 and 1968 — a fact that highlights the importance of the virulence of the virus subtype or genotype. Clinical, epidemiologic, and laboratory evidence suggests that a pandemic caused by the current H5N1 strain would be more likely to mimic the 1918 pandemic than those that occurred more recently.5 If we translate the rate of death associated with the 1918 influenzavirus to that in the current population, there could be 1.7 million deaths in the United States and 180 million to 360 million deaths globally. We have an extremely limited armamentarium with which to handle millions of cases of ARDS — one not much different from that available to the front-line medical corps in 1918.Is there anything we can do to avoid this course? The answer is a qualified yes that depends on how everyone, from world leaders to local elected officials, decides to respond. We need bold and timely leadership at the highest levels of the governments in the developed world; these governments must recognize the economic, security, and health threats posed by the next influenza pandemic and invest accordingly. The resources needed must be considered in the light of the eventual costs of failing to invest in such an effort. The loss of human life even in a mild pandemic will be devastating, and the cost of a world economy in shambles for several years can only be imagined.Sign up for the Weekly Table of Contents email.
Each week, receive an email with links to the articles published in the current week's issue of the New England Journal of Medicine.
https://www.nejm.org/doi/full/10.1056/NEJMp058068
Much respect for Mr. Osterholm. That man knows his stuff!
"It's a sad and beautiful world"-Roberto Benigni0 -
brianlux said:Lerxst1992 said:This doctor was just on CNN and wrote this article 15 years ago about the next pandemic. He pointed out the US is worse off now, because we have been down sizing our hospital capacity since 2005. Much in his article is strikingly accurate to what we are facing.
Preparing for the Next Pandemic
List of authors.- Michael T. Osterholm, Ph.D., M.P.H.
May 5, 2005
N Engl J Med 2005; 352:1839-1842
DOI: 10.1056/NEJMp058068Annual influenza epidemics are like Minnesota winters — all are challenges, but some are worse than others. No matter how well we prepare, some blizzards take quite a toll. Each year, despite our efforts to increase the rates of influenza vaccination in our most vulnerable populations, unpredictable factors largely determine the burden of influenza disease and related deaths. During a typical year in the United States, 30,000 to 50,000 persons die as a result of influenzavirus infection, and the global death toll is about 20 to 30 times as high as the toll in this country. We usually accept this outcome as part of the cycle of life. Only when a vaccine shortage occurs or young children die suddenly does the public demand that someone step forward to change the course of the epidemic. Unfortunately, the fragile and limited production capacity of our 1950s egg-based technology for producing influenza vaccine and the lack of a national commitment to universal annual influenza vaccination mean that influenza epidemics will continue to present a substantial public health challenge for the foreseeable future.
An influenza pandemic has always been a great global infectious-disease threat. There have been 10 pandemics of influenza A in the past 300 years. A recent analysis showed that the pandemic of 1918 and 1919 killed 50 million to 100 million people,1 and although its severity is often considered anomalous, the pandemic of 1830 through 1832 was similarly severe — it simply occurred when the world's population was smaller. Today, with a world population of 6.5 billion — more than three times that in 1918 — even a relatively “mild” pandemic could kill many millions of people.Influenza experts recognize the inevitability of another pandemic. When will it begin? Will it be caused by H5N1, the avian influenzavirus strain currently circulating in Asia? Will its effect rival that of 1918 or be more muted, as was the case in the pandemics of 1957 and 1968? Nobody knows.So how can we prepare? One key step is to rapidly ramp up research related to the production of an effective vaccine, as the Department of Health and Human Services is doing. In addition to clinical research on the immunogenicity of influenza vaccines, urgent needs include basic research on the ecology and biology of influenzaviruses, studies of the epidemiologic role of various animal and bird species, and work on early interventions and risk assessment.2 Equally urgent is the development of cell-culture technology for production of vaccine that can replace our egg-based manufacturing process. Today, making the 300 million doses of influenza vaccine needed annually worldwide requires more than 350 million chicken eggs and six or more months; a cell-culture approach may produce much higher antigen yields and be faster. After such a process was developed, we would also need assured industrial capacity to produce sufficient vaccine for the world's population during the earliest days of an emerging pandemic.Beyond research and development, we need a public health approach that includes far more than drafting of general plans, as several countries and states have done. We need a detailed operational blueprint of the best way to get through 12 to 24 months of a pandemic.What if the next pandemic were to start tonight? If it were determined that several cities in Vietnam had major outbreaks of H5N1 infection associated with high mortality, there would be a scramble to stop the virus from entering other countries by greatly reducing or even prohibiting foreign travel and trade. The global economy would come to a halt, and since we could not expect appropriate vaccines to be available for many months and we have very limited stockpiles of antiviral drugs, we would be facing a 1918-like scenario.Production of a vaccine would take a minimum of six months after isolation of the circulating strain, and given the capacity of all the current international vaccine manufacturers, supplies during those next six months would be limited to fewer than a billion monovalent doses. Since two doses may be required for protection, we could vaccinate fewer than 500 million people — approximately 14 percent of the world's population. And owing to our global “just-in-time delivery” economy, we would have no surge capacity for health care, food supplies, and many other products and services. For example, in the United States today, we have only 105,000 mechanical ventilators, 75,000 to 80,000 of which are in use at any given time for everyday medical care; during a garden-variety influenza season, more than 100,000 are required. In a pandemic, most patients with influenza who needed ventilation would not have access to it.We have no detailed plans for staffing the temporary hospitals that would have to be set up in high-school gymnasiums and community centers — and that might need to remain in operation for one or two years. Health care workers would become ill and die at rates similar to, or even higher than, those in the general public. Judging by our experience with the severe acute respiratory syndrome (SARS), some health care workers would not show up for duty. How would communities train and use volunteers? If the pandemic wave were spreading slowly enough, could immune survivors of an early wave, particularly health care workers, become the primary response corps?Health care delivery systems and managed-care organizations have done little planning for such a scenario. Who, for instance, would receive the extremely limited antiviral agents that will be available? We need to develop a national, and even an international, consensus on the priorities for the use of antiviral drugs well before the pandemic begins. In addition, we have no way of urgently increasing production of critical items such as antiviral drugs, masks for respiratory protection, or antibiotics for the treatment of secondary bacterial infections. Even under today's relatively stable operating conditions, eight different antiinfective agents are in short supply because of manufacturing problems. Nor do we have detailed plans for handling the massive number of dead bodies that would soon exceed our ability to cope with them.What if an H5N1 influenza pandemic began not now but a year from now? We would still need to plan with fervor for local nonmedical as well as medical preparedness. Planning for a pandemic must be on the agenda of every public health agency, school board, manufacturing plant, investment firm, mortuary, state legislature, and food distributor. Health professionals must become much more proficient in “risk communication,” so that they can effectively provide the facts — and acknowledge the unknowns — to a frightened population.3With another year of lead time, vaccine might have a more central role in our response. Although the manufacturing capacity would still be limited, strategies such as developing antigen-sparing formulations — that is, intradermal formulations that take advantage of copious numbers of dendritic cells for antigen processing or formulations including adjuvants to boost the immune response — might extend the vaccine supply. Urgent planning efforts are required to ensure that we have the syringes and other essential equipment, as well as the workforce, for effective delivery. Finally, a detailed plan for vaccine allocation will be needed — before the crisis, not during it.What if the pandemic were 10 years away and we embarked today on a worldwide influenza Manhattan Project aimed at producing and delivering a pandemic vaccine for everyone in the world soon after the onset of sustained human-to-human transmission? In this scenario, we just might make a real difference.The current system of producing and distributing influenza vaccine is broken, both technically and financially. The belief that we can greatly advance manufacturing technology and expand capacity in the normal course of increasing our annual vaccination coverage is flawed. At our current pace, it will take generations for meaningful advances to be made. Our goal should be to develop a new cell-culture–based vaccine that includes antigens that are present in all subtypes of influenzavirus, that do not change from year to year, and that can be made available to the entire world population. We need an international approach to public funding that will pay for the excess production capacity required during a pandemic.Today, public health experts and infectious-disease scientists do not know whether H5N1 avian influenzavirus threatens an imminent pandemic. Most indications, however, suggest that it is just a matter of time: witness the increasing number of H5N1 infections in humans and animals, the documentation of additional small clusters of cases suggestive of near misses with respect to sustained human-to-human transmission, the ongoing genetic changes in the H5N1 Z genotype that have increased its pathogenicity, and the existence in Asia of a genetic-reassortment laboratory — the mix of an unprecedented number of people, pigs, and poultry.It is sobering to realize that in 1968, when the most recent influenza pandemic occurred, the virus emerged in a China that had a human population of 790 million, a pig population of 5.2 million, and a poultry population of 12.3 million; today, these populations number 1.3 billion, 508 million, and 13 billion, respectively. Similar changes have occurred in the human and animal populations of other Asian countries, creating an incredible mixing vessel for viruses. Given this reality, as well as the exponential growth in foreign travel during the past 50 years, we must accept that a pandemic is coming — although whether it will be caused by H5N1 or by another novel strain remains to be seen..Should H5N1 become the next pandemic strain, the resultant morbidity and mortality could rival those of 1918, when more than half the deaths occurred among largely healthy people between 18 and 40 years of age and were caused by a virus-induced cytokine storm (see diagram) that led to the acute respiratory distress syndrome (ARDS).4 The ARDS-related morbidity and mortality in the pandemic of 1918 was on a different scale from those of 1957 and 1968 — a fact that highlights the importance of the virulence of the virus subtype or genotype. Clinical, epidemiologic, and laboratory evidence suggests that a pandemic caused by the current H5N1 strain would be more likely to mimic the 1918 pandemic than those that occurred more recently.5 If we translate the rate of death associated with the 1918 influenzavirus to that in the current population, there could be 1.7 million deaths in the United States and 180 million to 360 million deaths globally. We have an extremely limited armamentarium with which to handle millions of cases of ARDS — one not much different from that available to the front-line medical corps in 1918.Is there anything we can do to avoid this course? The answer is a qualified yes that depends on how everyone, from world leaders to local elected officials, decides to respond. We need bold and timely leadership at the highest levels of the governments in the developed world; these governments must recognize the economic, security, and health threats posed by the next influenza pandemic and invest accordingly. The resources needed must be considered in the light of the eventual costs of failing to invest in such an effort. The loss of human life even in a mild pandemic will be devastating, and the cost of a world economy in shambles for several years can only be imagined.Sign up for the Weekly Table of Contents email.
Each week, receive an email with links to the articles published in the current week's issue of the New England Journal of Medicine.
https://www.nejm.org/doi/full/10.1056/NEJMp058068
Much respect for Mr. Osterholm. That man knows his stuff!
_____________________________________SIGNATURE________________________________________________
Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
Didn't people on her attack China for stopping people speaking out about Corona?
***Hospitals are threatening to fire health-care workers who publicize their working conditions during the coronavirus pandemic -- and have in some cases followed through.“Hospitals are muzzling nurses and other health-care workers in an attempt to preserve their image,” said Ruth Schubert, a spokeswoman for the Washington State Nurses Association. “It is outrageous.”Hospitals have traditionally had strict media guidelines to protect patient privacy, urging staff to talk with journalists only through official public relations offices. But the pandemic has ushered in a new era, Schubert said.Privacy laws prohibit disclosing specific patient information, but they don’t bar discussing general working conditions.
/.../
NYU Langone Health employees received a notice Friday from Kathy Lewis, executive vice president of communications, saying that anyone who talked to the media without authorization would be “subject to disciplinary action, including termination.”New York’s Montefiore Health System requires staff get permission before speaking publicly, and sent a reminder in a March 17 newsletter that all media requests “must be shared and vetted” by the public relations department.“Associates are not authorized to interact with reporters or speak on behalf of the institution in any capacity, without pre-approval,” according to the policy, which was seen by Bloomberg News.
https://www.bloomberg.com/news/articles/2020-03-31/hospitals-tell-doctors-they-ll-be-fired-if-they-talk-to-press
"Mostly I think that people react sensitively because they know you’ve got a point"0 -
nvm"Mostly I think that people react sensitively because they know you’ve got a point"0
-
mickeyrat said:brianlux said:Lerxst1992 said:This doctor was just on CNN and wrote this article 15 years ago about the next pandemic. He pointed out the US is worse off now, because we have been down sizing our hospital capacity since 2005. Much in his article is strikingly accurate to what we are facing.
Preparing for the Next Pandemic
List of authors.- Michael T. Osterholm, Ph.D., M.P.H.
May 5, 2005
N Engl J Med 2005; 352:1839-1842
DOI: 10.1056/NEJMp058068Annual influenza epidemics are like Minnesota winters — all are challenges, but some are worse than others. No matter how well we prepare, some blizzards take quite a toll. Each year, despite our efforts to increase the rates of influenza vaccination in our most vulnerable populations, unpredictable factors largely determine the burden of influenza disease and related deaths. During a typical year in the United States, 30,000 to 50,000 persons die as a result of influenzavirus infection, and the global death toll is about 20 to 30 times as high as the toll in this country. We usually accept this outcome as part of the cycle of life. Only when a vaccine shortage occurs or young children die suddenly does the public demand that someone step forward to change the course of the epidemic. Unfortunately, the fragile and limited production capacity of our 1950s egg-based technology for producing influenza vaccine and the lack of a national commitment to universal annual influenza vaccination mean that influenza epidemics will continue to present a substantial public health challenge for the foreseeable future.
An influenza pandemic has always been a great global infectious-disease threat. There have been 10 pandemics of influenza A in the past 300 years. A recent analysis showed that the pandemic of 1918 and 1919 killed 50 million to 100 million people,1 and although its severity is often considered anomalous, the pandemic of 1830 through 1832 was similarly severe — it simply occurred when the world's population was smaller. Today, with a world population of 6.5 billion — more than three times that in 1918 — even a relatively “mild” pandemic could kill many millions of people.Influenza experts recognize the inevitability of another pandemic. When will it begin? Will it be caused by H5N1, the avian influenzavirus strain currently circulating in Asia? Will its effect rival that of 1918 or be more muted, as was the case in the pandemics of 1957 and 1968? Nobody knows.So how can we prepare? One key step is to rapidly ramp up research related to the production of an effective vaccine, as the Department of Health and Human Services is doing. In addition to clinical research on the immunogenicity of influenza vaccines, urgent needs include basic research on the ecology and biology of influenzaviruses, studies of the epidemiologic role of various animal and bird species, and work on early interventions and risk assessment.2 Equally urgent is the development of cell-culture technology for production of vaccine that can replace our egg-based manufacturing process. Today, making the 300 million doses of influenza vaccine needed annually worldwide requires more than 350 million chicken eggs and six or more months; a cell-culture approach may produce much higher antigen yields and be faster. After such a process was developed, we would also need assured industrial capacity to produce sufficient vaccine for the world's population during the earliest days of an emerging pandemic.Beyond research and development, we need a public health approach that includes far more than drafting of general plans, as several countries and states have done. We need a detailed operational blueprint of the best way to get through 12 to 24 months of a pandemic.What if the next pandemic were to start tonight? If it were determined that several cities in Vietnam had major outbreaks of H5N1 infection associated with high mortality, there would be a scramble to stop the virus from entering other countries by greatly reducing or even prohibiting foreign travel and trade. The global economy would come to a halt, and since we could not expect appropriate vaccines to be available for many months and we have very limited stockpiles of antiviral drugs, we would be facing a 1918-like scenario.Production of a vaccine would take a minimum of six months after isolation of the circulating strain, and given the capacity of all the current international vaccine manufacturers, supplies during those next six months would be limited to fewer than a billion monovalent doses. Since two doses may be required for protection, we could vaccinate fewer than 500 million people — approximately 14 percent of the world's population. And owing to our global “just-in-time delivery” economy, we would have no surge capacity for health care, food supplies, and many other products and services. For example, in the United States today, we have only 105,000 mechanical ventilators, 75,000 to 80,000 of which are in use at any given time for everyday medical care; during a garden-variety influenza season, more than 100,000 are required. In a pandemic, most patients with influenza who needed ventilation would not have access to it.We have no detailed plans for staffing the temporary hospitals that would have to be set up in high-school gymnasiums and community centers — and that might need to remain in operation for one or two years. Health care workers would become ill and die at rates similar to, or even higher than, those in the general public. Judging by our experience with the severe acute respiratory syndrome (SARS), some health care workers would not show up for duty. How would communities train and use volunteers? If the pandemic wave were spreading slowly enough, could immune survivors of an early wave, particularly health care workers, become the primary response corps?Health care delivery systems and managed-care organizations have done little planning for such a scenario. Who, for instance, would receive the extremely limited antiviral agents that will be available? We need to develop a national, and even an international, consensus on the priorities for the use of antiviral drugs well before the pandemic begins. In addition, we have no way of urgently increasing production of critical items such as antiviral drugs, masks for respiratory protection, or antibiotics for the treatment of secondary bacterial infections. Even under today's relatively stable operating conditions, eight different antiinfective agents are in short supply because of manufacturing problems. Nor do we have detailed plans for handling the massive number of dead bodies that would soon exceed our ability to cope with them.What if an H5N1 influenza pandemic began not now but a year from now? We would still need to plan with fervor for local nonmedical as well as medical preparedness. Planning for a pandemic must be on the agenda of every public health agency, school board, manufacturing plant, investment firm, mortuary, state legislature, and food distributor. Health professionals must become much more proficient in “risk communication,” so that they can effectively provide the facts — and acknowledge the unknowns — to a frightened population.3With another year of lead time, vaccine might have a more central role in our response. Although the manufacturing capacity would still be limited, strategies such as developing antigen-sparing formulations — that is, intradermal formulations that take advantage of copious numbers of dendritic cells for antigen processing or formulations including adjuvants to boost the immune response — might extend the vaccine supply. Urgent planning efforts are required to ensure that we have the syringes and other essential equipment, as well as the workforce, for effective delivery. Finally, a detailed plan for vaccine allocation will be needed — before the crisis, not during it.What if the pandemic were 10 years away and we embarked today on a worldwide influenza Manhattan Project aimed at producing and delivering a pandemic vaccine for everyone in the world soon after the onset of sustained human-to-human transmission? In this scenario, we just might make a real difference.The current system of producing and distributing influenza vaccine is broken, both technically and financially. The belief that we can greatly advance manufacturing technology and expand capacity in the normal course of increasing our annual vaccination coverage is flawed. At our current pace, it will take generations for meaningful advances to be made. Our goal should be to develop a new cell-culture–based vaccine that includes antigens that are present in all subtypes of influenzavirus, that do not change from year to year, and that can be made available to the entire world population. We need an international approach to public funding that will pay for the excess production capacity required during a pandemic.Today, public health experts and infectious-disease scientists do not know whether H5N1 avian influenzavirus threatens an imminent pandemic. Most indications, however, suggest that it is just a matter of time: witness the increasing number of H5N1 infections in humans and animals, the documentation of additional small clusters of cases suggestive of near misses with respect to sustained human-to-human transmission, the ongoing genetic changes in the H5N1 Z genotype that have increased its pathogenicity, and the existence in Asia of a genetic-reassortment laboratory — the mix of an unprecedented number of people, pigs, and poultry.It is sobering to realize that in 1968, when the most recent influenza pandemic occurred, the virus emerged in a China that had a human population of 790 million, a pig population of 5.2 million, and a poultry population of 12.3 million; today, these populations number 1.3 billion, 508 million, and 13 billion, respectively. Similar changes have occurred in the human and animal populations of other Asian countries, creating an incredible mixing vessel for viruses. Given this reality, as well as the exponential growth in foreign travel during the past 50 years, we must accept that a pandemic is coming — although whether it will be caused by H5N1 or by another novel strain remains to be seen..Should H5N1 become the next pandemic strain, the resultant morbidity and mortality could rival those of 1918, when more than half the deaths occurred among largely healthy people between 18 and 40 years of age and were caused by a virus-induced cytokine storm (see diagram) that led to the acute respiratory distress syndrome (ARDS).4 The ARDS-related morbidity and mortality in the pandemic of 1918 was on a different scale from those of 1957 and 1968 — a fact that highlights the importance of the virulence of the virus subtype or genotype. Clinical, epidemiologic, and laboratory evidence suggests that a pandemic caused by the current H5N1 strain would be more likely to mimic the 1918 pandemic than those that occurred more recently.5 If we translate the rate of death associated with the 1918 influenzavirus to that in the current population, there could be 1.7 million deaths in the United States and 180 million to 360 million deaths globally. We have an extremely limited armamentarium with which to handle millions of cases of ARDS — one not much different from that available to the front-line medical corps in 1918.Is there anything we can do to avoid this course? The answer is a qualified yes that depends on how everyone, from world leaders to local elected officials, decides to respond. We need bold and timely leadership at the highest levels of the governments in the developed world; these governments must recognize the economic, security, and health threats posed by the next influenza pandemic and invest accordingly. The resources needed must be considered in the light of the eventual costs of failing to invest in such an effort. The loss of human life even in a mild pandemic will be devastating, and the cost of a world economy in shambles for several years can only be imagined.Sign up for the Weekly Table of Contents email.
Each week, receive an email with links to the articles published in the current week's issue of the New England Journal of Medicine.
https://www.nejm.org/doi/full/10.1056/NEJMp058068
Much respect for Mr. Osterholm. That man knows his stuff!
Oh man, YES! Heavy duty interview. And Rogan... the poor guy was sweating bullets.
"It's a sad and beautiful world"-Roberto Benigni0 -
"Mostly I think that people react sensitively because they know you’ve got a point"0
-
Spiritual_Chaos said:Didn't people on her attack China for stopping people speaking out about Corona?
***Hospitals are threatening to fire health-care workers who publicize their working conditions during the coronavirus pandemic -- and have in some cases followed through.“Hospitals are muzzling nurses and other health-care workers in an attempt to preserve their image,” said Ruth Schubert, a spokeswoman for the Washington State Nurses Association. “It is outrageous.”Hospitals have traditionally had strict media guidelines to protect patient privacy, urging staff to talk with journalists only through official public relations offices. But the pandemic has ushered in a new era, Schubert said.Privacy laws prohibit disclosing specific patient information, but they don’t bar discussing general working conditions.
/.../
NYU Langone Health employees received a notice Friday from Kathy Lewis, executive vice president of communications, saying that anyone who talked to the media without authorization would be “subject to disciplinary action, including termination.”New York’s Montefiore Health System requires staff get permission before speaking publicly, and sent a reminder in a March 17 newsletter that all media requests “must be shared and vetted” by the public relations department.“Associates are not authorized to interact with reporters or speak on behalf of the institution in any capacity, without pre-approval,” according to the policy, which was seen by Bloomberg News.
https://www.bloomberg.com/news/articles/2020-03-31/hospitals-tell-doctors-they-ll-be-fired-if-they-talk-to-press
_____________________________________SIGNATURE________________________________________________
Not today Sir, Probably not tomorrow.............................................. bayfront arena st. pete '94
you're finally here and I'm a mess................................................... nationwide arena columbus '10
memories like fingerprints are slowly raising.................................... first niagara center buffalo '13
another man ..... moved by sleight of hand...................................... joe louis arena detroit '140 -
One of the reasons Peesident Trump doesn't seem to be his usual self is simply because he doesn't currently have a scandal hanging over his orange head.
Peace*We CAN bomb the World to pieces, but we CAN'T bomb it into PEACE*...Michael Franti
*MUSIC IS the expression of EMOTION.....and that POLITICS IS merely the DECOY of PERCEPTION*
.....song_Music & Politics....Michael Franti
*The scientists of today think deeply instead of clearly. One must be sane to think clearly, but one can think deeply and be quite INSANE*....Nikola Tesla(a man who shaped our world of electricity with his futuristic inventions)0 -
Already in September, it is hoped to be able to start trials on people and the goal is to have a corona vaccine completed early in 2021."I do not believe that"Matti Sällberg is a professor of biomedical analysis at the Karolinska Institutet in Stockholm and does not believe that Johnson & Johnson is likely to complete a vaccine in such a short time.- I do not believe that. If they start doing Phase 1 studies this fall, it would be impossible to have a vaccine ready by the beginning of next year, but instead rather by the end of that year. Under the assumption that safety data from animal studies is good. If it's not good, then their schedule will crash, says Matti Sällberg."Mostly I think that people react sensitively because they know you’ve got a point"0
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Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:CM189191 said:Thoughts_Arrive said:F Me In The Brain said:You walk right back in and piss around about China.
Nothing has changed.
Do you live there? Are you of Chinese background?
Did you read what I shared in that article and did you watch that video?
Why are you not allowing me to be critical of China? Why are you criticising me for criticising China?
So you have no issue with their secrecy which led to thousands of innocent people dying around the world?
Why did they not alert the WHO and other countries and stop flights leaving Wuhan when they first knew of this new virus? Doing so would have prevented this outbreak.
I don't understand you and others here.
I'd be more than glad to buy Australian made clothes and appliances. Even if I have to pay more.
This is the world's fault for being greedy (in wanting cheap labour).
You pay more for domestic goods. And the North Korean people suffer under an oppressive regime. It's economic inequality on a massive multinational scale.
Staying in the TPP agreement would have been a good start...0
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