Epigenetics

124678

Comments

  • Jeanie
    Jeanie Posts: 9,446
    MahoganySouls wrote:
    good points. Yes medicine is called a "practice" for a reason. Understanding is always evolving. This too coincides though with the idea from the video that what we do now, the mistakes we might make now, effects us presently, our children and umpteen generations to come.

    Yes. :) I appreciate that what I am told at my doctor today may not be what they tell me 5 years or 10 years from now. And that's fine by me as long as I'm not being "blamed" for their inability to work something out. I'm not saying that is always the case because of course it is not, but there are more than enough doctors and health care professionals with a "blame the patient" mentality. I even understand why they come to hold that view. But bearing in mind, that "mistakes" are just that, things that we do wrong without intention and also bearing in mind that it will not just be individual mistakes that will affect us epigenetically for generations but also the "mistakes" or possibly even the intentions of a lot of outside contributors, then while I welcome this advancement I think we are a long way from being able to prevent all disease, and sickness for generations.
    NOPE!!!

    *~You're IT Bert!~*

    Hold on to the thread
    The currents will shift
  • gue_barium
    gue_barium Posts: 5,515
    There used to be a guy on this board named "Epi."

    He was the funniest fucker....

    I think he got banned for life for telling suicidal people to kill themselves.
    all posts by ©gue_barium are protected under US copyright law and are not to be reproduced, exchanged or sold
    except by express written permission of ©gue_barium, the author.
  • Marbles
    Marbles Posts: 49
    MahoganySouls wrote:
    such as? You could be highly intelligent and still be autistic. The two do not equate. Most savants fall into the autistic spectrum. However, I would still acertain that the majority of autistics would give up any residual intellect from their disease if they could rid themselves of its negative aspects.
    By the new, sweepingly broad definitions of the spectrum, almost anyone in a math or science major in college is "on the spectrum". That is bull. Being analytical, and not preoccupied with socialization is not a pathology!
  • Marbles
    Marbles Posts: 49
    Ahnimus wrote:
    As usual, I'm not interested theories that are based solely on personal experience or conjecture. You seem to ascribe to what is often called the naturalistic fallacy, the belief that moral oughts can be derived from a natural is, or the is-ought problem of David Hume.[1][2].

    Morality seems to arise as a human construct from a number of functions our brains perform....
    I'm not tying it to morality, but we have kept people alive in the past few generations that would not have lived without intervention. Critters that were going to die, that have been saved are to be expected to have some complications. Look at the products of the quack fertility doctors that routinely produce high order multiples. These children more often than not suffer serious medical repercussions for life. (One also has to wonder WHY the couple was originally unable to reproduce. What was wrong that kept them from producing viable offspring?) Protecting the weak, and producing more of the weak will weaken the species, but I'm not going to ask for regulation of breeding.
  • MahoganySouls
    MahoganySouls Posts: 357
    Marbles wrote:
    Being analytical, and not preoccupied with socialization is not a pathology!
    no it is not...but Autism is not that simply diagnosed.
    "When you're climbing to the top, you'd better know the way back down" MSB
  • Ahnimus
    Ahnimus Posts: 10,560
    Marbles wrote:
    I'm not tying it to morality, but we have kept people alive in the past few generations that would not have lived without intervention. Critters that were going to die, that have been saved are to be expected to have some complications. Look at the products of the quack fertility doctors that routinely produce high order multiples. These children more often than not suffer serious medical repercussions for life. (One also has to wonder WHY the couple was originally unable to reproduce. What was wrong that kept them from producing viable offspring?) Protecting the weak, and producing more of the weak will weaken the species, but I'm not going to ask for regulation of breeding.

    Chances are we'd be extinct if we didn't help the weak. We are a physically weak species in general. Known genetics accounts for 25% of all obesity. To me, it's not a catagorical system, you've seen how complex metabolism is. All of life is so complex and we aren't exactly free of the law of conservation mass-energy.
    I necessarily have the passion for writing this, and you have the passion for condemning me; both of us are equally fools, equally the toys of destiny. Your nature is to do harm, mine is to love truth, and to make it public in spite of you. - Voltaire
  • Ahnimus
    Ahnimus Posts: 10,560
    baraka wrote:

    http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16926531&query_hl=3&itool=pubmed_docsum

    Without a subscription, you only get the abstract, but this gives you the 'meat' of the matter.

    Great, I just need some potatos, gravy, some veggies and I'm all set for dinner.

    This link says something about histamine being involved in high-fat diet (HFD). Does this suggest that people taking antihistamines regularly are at risk of obesity?
    I necessarily have the passion for writing this, and you have the passion for condemning me; both of us are equally fools, equally the toys of destiny. Your nature is to do harm, mine is to love truth, and to make it public in spite of you. - Voltaire
  • baraka
    baraka Posts: 1,268
    MahoganySouls wrote:
    As a "medical professional" myself, I am highly against immunizations in children. As mentioned in an earlier post, from my studies, I have concluded that the increase in Autism, Aspergers and ADHD are directly linked to the shots given routinely to kids.

    MahoganySouls, I'm curious, what kind of 'studies' have you performed in your role as a 'medical professional'? Did you perform professional research in this area? Are you against ALL immunizations?
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • baraka
    baraka Posts: 1,268
    Ahnimus wrote:
    Great, I just need some potatos, gravy, some veggies and I'm all set for dinner.

    This link says something about histamine being involved in high-fat diet (HFD). Does this suggest that people taking antihistamines regularly are at risk of obesity?

    Ha ha... I just took an antihistamine and hour ago and just now ate a piece of pizza! Interesting question, Ahnimus and I don't know the answer to that. From personal experience, I take an antihistamine regularly (almost daily, not so much in the winter) and I do not watch what I eat at all, however, I do not eat very large portions. I do not have a weight problem. But you've made me paranoid now! ;)
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • baraka
    baraka Posts: 1,268
    MahoganySouls wrote:
    So then you disagree with the thermosal argument?

    All pediatric vaccines in the routine infant immunization schedule are manufactured without thimerosal as a preservative as of 2003, I believe.

    From the CDC: http://www.cdc.gov/od/science/iso/thimerosal.htm

    "Today, with the exception of some Influenza (flu) vaccines, none of the vaccines used in the U.S. to protect preschool children against 12 infectious diseases contain thimerosal as a preservative."
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • Ahnimus
    Ahnimus Posts: 10,560
    baraka wrote:
    Ha ha... I just took an antihistamine and hour ago and just now ate a piece of pizza! Interesting question, Ahnimus and I don't know the answer to that. From personal experience, I take an antihistamine regularly (almost daily, not so much in the winter) and I do not watch what I eat at all, however, I do not eat very large portions. I do not have a weight problem. But you've made me paranoid now! ;)

    It sounds like antihistamines work on the histamine receptors of certain tissues and don't affect metabolism. So I gathered with my limited understanding.
    I necessarily have the passion for writing this, and you have the passion for condemning me; both of us are equally fools, equally the toys of destiny. Your nature is to do harm, mine is to love truth, and to make it public in spite of you. - Voltaire
  • Jeanie
    Jeanie Posts: 9,446
    Ahnimus wrote:
    It sounds like antihistamines work on the histamine receptors of certain tissues and don't affect metabolism. So I gathered with my limited understanding.

    Yeah, but Ryan, isn't it possible that antihistamines could work differently on different people? And quite possibly could effect metabolism in some?

    Not saying either way, just curious.
    NOPE!!!

    *~You're IT Bert!~*

    Hold on to the thread
    The currents will shift
  • baraka
    baraka Posts: 1,268
    Ahnimus wrote:
    It sounds like antihistamines work on the histamine receptors of certain tissues and don't affect metabolism. So I gathered with my limited understanding.

    Impressive Ahnimus. You're right http://health.discovery.com/centers/articles/articles.html?chrome=c02&article=LC_55&center=p01

    I'll tell you one thing. They sure you tired. I just got up from a nap and I'm still in a mental fog!
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • baraka
    baraka Posts: 1,268
    Jeanie wrote:
    Yeah, but Ryan, isn't it possible that antihistamines could work differently on different people? And quite possibly could effect metabolism in some?

    Not saying either way, just curious.


    According to the link I just provided Ahnimus, antihistamines 'coat' the receptor sites of histamines preventing the histamine from binding and causing inflamation, congestion, etc. It doesn't bind to the histamine directly or decrease histamine levels as far I can tell. The specific article I posted earlier indicated a correlation of decreased histamine levels to increased high fat diet induced obesity.
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • gue_barium
    gue_barium Posts: 5,515
    baraka wrote:
    Impressive Ahnimus. You're right http://health.discovery.com/centers/articles/articles.html?chrome=c02&article=LC_55&center=p01

    I'll tell you one thing. They sure you tired. I just got up from a nap and I'm still in a mental fog!

    You tired sure is.
    all posts by ©gue_barium are protected under US copyright law and are not to be reproduced, exchanged or sold
    except by express written permission of ©gue_barium, the author.
  • baraka
    baraka Posts: 1,268
    gue_barium wrote:
    You tired sure is.

    Lol! Did I really write that? Ok, they make you stupid.........
    The greatest obstacle to discovery is not ignorance,
    but the illusion of knowledge.
    ~Daniel Boorstin

    Only a life lived for others is worth living.
    ~Albert Einstein
  • Ahnimus
    Ahnimus Posts: 10,560
    baraka wrote:
    Impressive Ahnimus. You're right http://health.discovery.com/centers/articles/articles.html?chrome=c02&article=LC_55&center=p01

    I'll tell you one thing. They sure [make] you tired. I just got up from a nap and I'm still in a mental fog!

    Haha, thanks. It took me awhile to figure out the 3rd sentence there, but I think I got it ;)

    I used to take antihistamines for sleep because of my allergy to dust mites. But now I just have a cover I wash regularly.
    I necessarily have the passion for writing this, and you have the passion for condemning me; both of us are equally fools, equally the toys of destiny. Your nature is to do harm, mine is to love truth, and to make it public in spite of you. - Voltaire
  • Ahnimus
    Ahnimus Posts: 10,560
    Jeanie wrote:
    Yeah, but Ryan, isn't it possible that antihistamines could work differently on different people? And quite possibly could effect metabolism in some?

    Not saying either way, just curious.

    What I've been reading is that antihistmaines act on H1 histamine receptors, there are also H2, H3, and H4 histamine receptors. I've also read that all anthistamines permeate the blood-brain barrier. H1 receptors are invovled in vasodilation, bronchoconstriction, smooth muscle activation, separation of endothelial cells (responsible for hives), and pain and itching due to insect stings; the primary receptors involved in allergic rhinitis symptoms and motion sickness. But, I haven't found which histamine receptors are involved in metabolism.
    I necessarily have the passion for writing this, and you have the passion for condemning me; both of us are equally fools, equally the toys of destiny. Your nature is to do harm, mine is to love truth, and to make it public in spite of you. - Voltaire
  • Jeanie
    Jeanie Posts: 9,446
    baraka wrote:
    According to the link I just provided Ahnimus, antihistamines 'coat' the receptor sites of histamines preventing the histamine from binding and causing inflamation, congestion, etc. It doesn't bind to the histamine directly or decrease histamine levels as far I can tell. The specific article I posted earlier indicated a correlation of decreased histamine levels to increased high fat diet induced obesity.

    I'm half asleep, so didn't notice the link barak. :) thanks. I'll go back and read it. although I can't imagine that it's gonna sink in even remotely today. :o
    NOPE!!!

    *~You're IT Bert!~*

    Hold on to the thread
    The currents will shift
  • Jeanie
    Jeanie Posts: 9,446
    baraka wrote:
    Lol! Did I really write that? Ok, they make you stupid.........

    Well I doubt they make you stupid, perhaps they just make you look stupid? ;)
    NOPE!!!

    *~You're IT Bert!~*

    Hold on to the thread
    The currents will shift

Categories