The coronavirus

oftenreading · March 2021

Meltdown99 said:

HughFreakingDillon said:

Meltdown99 said:

HughFreakingDillon said:

lastexitlondon said:

Meltdown99 said:

lastexitlondon said:

Meltdown99 said:

PJNB said:

I would also say that it makes sense in a dense population that is overrun by the virus and they need some kind of protection with limited supplies of the vaccine to space it out to get some relief. Not for a province that is regarded as one of the best places to be in NA during this virus (largely based on small population). Protect all of the vulnerable with the recommended dose. 16 weeks spaced out imo will lead a lot more people to say fuck it i do not need the second dose in the summer when things are way more calmed down.

It’s always best to follow the manufacturers instructions...

They are spreading the dose out so the prime minister and some premiers can save face...

And really, I’m not surprised...our health care is rationed at the best of times.

The manufacturers did not test a longer gap but we the UK have in real time and its conclusive.

No it’s not.

What are you on about?I live in the UK and it's happening here . What part is not conclusive. Look if you keep searching you will find someone that agrees. But seriously the immunity grows day upon day and infact the second dose is too soon as it only adds a minor percentage. The first dose keeps growing after the 21 days and even more after 30 odd days. Meaning the trials dis NOT allow for a longer gap . Now its proven. Believe what you like. People can believe what they like but science is fact

it's not a fact to him unless it proves canadian politicians are corrupt and/or stupid.

You don’t know anything about me. Your just a troll...and you know it. You’ve trolled me for quite a while. Why is that?

Do you ever post facts and links...or do you just believe anything lying corrupt politicians tell-you? All sides. It’s doubtful.

I'm a troll. BWAHAHAHAHAHAHA. good one.

I don't troll you. I have you on ignore. I only see your posts if someone else quotes it. try again. I only checked this post because I knew it would be some bitter post about me.

I believe science. that's it. SCIENCE.

oh, and it's "you're".

LMFAO. I believe in Science. Lmfao. Yeah sure you do. Then post something to back up your claim? To bad you didn’t believe in good government and clean drinking ...

you are (is that better...) like most Canadians will waste your vote on either liberal of con...same old.

I am at least willing to give SINGH A chance? Maybe he will make an effort to get clean drinking water to ALL Canadians...

your such an arrogant person...go troll someone else.

I voted NDP in the last federal election. The candidate got elected, too.

That doesn’t make a damn bit of difference to the discussion about covid though.

lastexitlondon · March 2021

https://youtu.be/md8pJFbMVnk
The first part of this is an interesting theory about the clots. Makes sence. Is in the administering into a vein by mistake maybe

lastexitlondon · March 2021

I was talking to my Dr and he was saying he is head of the vaccine roll out in our area and the health minister zoom called him to congratulate him personally. But what i found interesting was he said they had AZ with a red top which was military grade. Wtf does that mean.

lastexitlondon · March 2021

I'm watching the news and Brazil is really in trouble with this. 300.000 dead and running out of oxygen my heart is so heavy seeing the idiot president there basically dismissed masks and the lack of any lockdowns plus variant they look fucked.
Why is the world responding so different?

Zod · March 2021

lastexitlondon said:

I'm watching the news and Brazil is really in trouble with this. 300.000 dead and running out of oxygen my heart is so heavy seeing the idiot president there basically dismissed masks and the lack of any lockdowns plus variant they look fucked.
Why is the world responding so different?

A combination of leadership, population density, capacity, and percentage of population that is unreasonable? You need a leader that can make hard choices, the more population dense your country is the harder it's going to be, and you need the Financial Capacity to weather the storm. You also need the capacity to buy or manufacture vaccines.

Not all countries have these things (or any of them)

lastexitlondon · March 2021

Its very sad indeed

oftenreading · March 2021

We don't yet know enough about the need for vaccinating people who have already had covid but the current recommendation is that they be vaccinated. There is some recent preliminary data to suggest that they may only need one shot to really boost their immune response.

https://nationalpost.com/news/had-covid-if-youre-younger-one-dose-of-vaccine-might-be-enough

Had COVID? If you're younger, one dose of vaccine might be enough

Author of the article:

Sharon Kirkey

Publishing date:

Mar 23, 2021 • 2 days ago •

Weeks after saying COVID-19 vaccine doses could be spaced out up to four months apart, a national expert advisory group is now deliberating whether one shot alone is sufficient for people who have had COVID.

Several recent small studies suggest that a single dose of the Pfizer/BioNTech or Moderna shots can launch a rapid immune response in people previously infected with the pandemic virus.

The response is so strong, people with a known history of COVID are reporting vaccine side effects — fever, headache, chills and muscle and joint pain — more frequently than the never infected after the first dose. Normally, the second dose tends to be more prone to side effects.

“Somebody who has had COVID before seems to respond very quickly to a dose of vaccine,” said Dr. Caroline Quach-Thanh, a pediatric infectious disease specialist at the University of Montreal and co-chair of Canada’s National Advisory Committee on Immunization, or NACI.

“They respond as a naïve person would with their second shot,” Quach-Thanh said.

“The question that remains is that a one-size-fits-all for every previous infection? If you were asymptomatic at first infection, is it still OK?”

Also not clear is whether a single dose would be sufficient for older people who were previously infected or those with compromised immune systems.

But a one-dose-after-COVID strategy, as France’s top health authority, and now Quebec, has recommended, could stretch vaccine supplies and, while the vaccines are generally well tolerated, spare people unnecessary side effects of a second dose, researchers said.

One small study found that after the first dose of the Pfizer or Moderna vaccines, antibody titers — the amount of antibodies within a person’s blood — of previously infected “vaccinees” were 10 to 45 times as high as those of vaccinees without previous immunity when measured at the same time points after the first dose. For example, 13 to 16 days post-first dose, they were 25 times as high.

And while the antibody concentrations of people who had never been infected increased by a factor of three after the second shot, “no increase in antibody titers was observed in the COVID-19 survivors who received the second vaccine dose,” the researchers from the Icahn School of Medicine at Mount Sinai in New York wrote, suggesting that a booster or second dose might be of little value.

What explains the stronger response in the previously infected? The Pfizer and Moderna vaccines are both messenger RNA vaccines. They work by instructing the body’s cells to produce a piece of the spike-shaped protein that adorns the surface of the virus that causes COVID.

That triggers an immune response and, in response, the body produces antibodies to protect people from getting infected if the real virus enters their bodies.

If the body has already been primed by a past infection to recognize the spike protein, the immune cells respond more vigorously after the first shot of vaccine.

“There’s certainly the suggestion that if you have previously been infected, it’s kind of like having had your first dose” of vaccine, said Toronto infectious diseases specialist Dr. Andrew Morris.

The problem is that it’s not yet known how long those early differences in immune responses last or whether the same would hold true for older people. The Mount Sinai study involved mostly younger (mean age 40) healthy adults.

It’s also not known how durable the vaccine-based immune response will be. Six months? Longer? Less?

Quach-Thanh said the panel’s controversial decision taken earlier this month to recommend spacing shots out to up to 16 weeks to give more people a first dose now makes this “less of an emergency situation to tackle.” However, she said Quebec recently changed its approach, and now “anybody who had a previously confirmed COVID infection is only getting one dose of vaccine,” though the immunocompromised will still receive two.

But Quach-Thanh said most experts expect booster shots will become the norm in the future. It won’t be a matter of one and forever done. “Call it a booster dose, call it new vaccine against variants, call it whatever you want.”

There have been 941,000 confirmed infections in Canada, though the true number could be four times, even 10 times higher, based on how much testing is being done.

The Mount Sinai researchers suggested screening people for antibodies, if their infection history isn’t known. Others argue testing everyone for antibodies would seriously bog down the process. Rapid antibody tests can also produce false positive.

People could also have lower antibody levels after a COVID infection if they had mild or no symptoms. If someone was just found to be COVID-positive because there was mass screening in a long-term care facility they worked in, they may still need two full doses, Quach-Thanh suggested. “Will the response to a first dose of vaccine be the same for everybody who has had a COVID infection before, regardless of the severity of disease?”

A large study from Denmark suggests that a prior COVID infection gives people around 80 per cent protection again re-infection, though protection was only 47 per cent for people 65 and older.

Still, reinfection can happen, Morris said — “it’s not as rare as people think” — and mutations are increasing the risk, making it important that people who have already caught COVID be vaccinated.

For younger people, a one-dose strategy may be a reasonable approach, “but I think we need more data,” Morris said.

“For older people, I think it’s really unknown, and I think assuming you could get away with it is probably not necessarily so wise.”

In Quebec, “I cannot tell you what will happen if someone really wants the second dose — will it be offered or not? In the end it’s not dangerous, it’s not a contraindication to receive two doses,” said Dr. Nicholas Brousseau, chair of Quebec’s immunization committee. “It’s just not necessary, and the dose will be better used as a second dose for people who didn’t have COVID-19.”

23scidoo · March 2021

But i thought those pharmaceutical companies they care for us..

https://verietyinfo.com/bulgariaeng/they-found-29-million-doses-of-astrazeneca-vaccine-at-a-plant-in-italy/

lastexitlondon · March 2021

The companies don't care brother thats well known

Hobbes · March 2021

Everybody nose...

https://twitter.com/thehill/status/1375052108563628037?s=20

Halifax2TheMax · March 2021

Hobbes said:

Everybody nose...

https://twitter.com/thehill/status/1375052108563628037?s=20

How’d she get Wobbit’s undergarments? Wobbit!

23scidoo · March 2021

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Hobbes · March 2021

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

The breadth of science is not limited simply to pharmaceutical companies.

lastexitlondon · March 2021

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Yes definitely trust science. It's the best we have. Pharma is money . Different things

23scidoo · March 2021

Hobbes said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

The breadth of science is not limited simply to pharmaceutical companies.

lastexitlondon said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Yes definitely trust science. It's the best we have. Pharma is money . Different things

Disagree..at this point the whole planet dance and they play the music..

Merkin Baller · March 2021

I trust the science more than I trust trolls on the PJ forum, that's for God damn sure.

dignin · March 2021

23scidoo said:

Hobbes said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

The breadth of science is not limited simply to pharmaceutical companies.

lastexitlondon said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Yes definitely trust science. It's the best we have. Pharma is money . Different things

Disagree..at this point the whole planet dance and they play the music..

Your ignorance is astounding.

How can anyone even begin to have a rational conversation with someone who believes that a pharmaceutical company equals science.

I just hope nobody here takes your nonsense seriously.

hedonist · March 2021

lastexitlondon said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Yes definitely trust science. It's the best we have. Pharma is money . Different things

Amen to that, Rob.

dankind · March 2021

dignin said:

23scidoo said:

Hobbes said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

The breadth of science is not limited simply to pharmaceutical companies.

lastexitlondon said:

23scidoo said:

lastexitlondon said:

The companies don't care brother thats well known

But my friend all i read here is this..''trust the science!!''
people like to sleep and dream..

Yes definitely trust science. It's the best we have. Pharma is money . Different things

Disagree..at this point the whole planet dance and they play the music..

Your ignorance is astounding.

How can anyone even begin to have a rational conversation with someone who believes that a pharmaceutical company equals science.

I just hope nobody here takes your nonsense seriously.

How many Big Pharma CEOs actually have advanced degrees in biochemistry or a related field?

Is it more than zero?

I'll wait....

Hobbes · March 2021

Thankfully those in the scientific community that conduct the research, testing, etc. do have advanced degrees.

The coronavirus

Comments

Had COVID? If you're younger, one dose of vaccine might be enough

Weeks after saying COVID-19 vaccine doses could be spaced out up to four months apart, a national expert advisory group is now deliberating whether one shot alone is sufficient for people who have had COVID.

“They respond as a naïve person would with their second shot,” Quach-Thanh said.

A large study from Denmark suggests that a prior COVID infection gives people around 80 per cent protection again re-infection, though protection was only 47 per cent for people 65 and older.

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